Clinicians – Communicable Diseases Research

Prepandemic Alzheimer Disease Biomarkers and Anxious-Depressive Symptoms During the COVID-19 Confinement in Cognitively Unimpaired Adults

Article

Published on 2022-10-042022-11-15
Journal: Neurology
[Category] 바이오마커,

Integrating basic science with translational research: the 13th International Podocyte Conference 2021

Short communication

Published on 2022-10-012022-10-05
Journal: Kidney international
[Category] 비임상,

[키워드] 13th International Podocyte Conference Abstract addition Basic science Clinicians Conference coronavirus disease COVID-19 Day Diagnosis global pandemic introduced meeting report offered pandemic pathway Patient patients podocyte podocyte2021 Research researcher researchers Resilience selected Therapies translational
[DOI] 10.1016/j.kint.2022.07.021 [Article Type] Short communication

Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system

Article

Published on 2022-09-212022-11-15
Journal: Cardiovascular Diabetology
[Category] 바이오마커, 유전자 메커니즘, 진단,

[키워드] absence addition analysed antibodies Anxiety Biomarker C-reactive protein cardiovascular disease Chronic fatigue circulation Clinicians Cognitive impairment Cohort Comorbidities Confusion contribute controls COVID COVID patient COVID-19 Depression detect disease Dyspnoea Evidence explain Failed fibrinolysis fatigue fibrinogen fibrinolytic system granular Health healthy controls Host immune response IL-6 implication increased risk individual Inflammatory inflammatory markers insoluble Kallikrein Long Long COVID mechanism Microclots PASC pathology Patient PF4 plasma Platelet platelet factor 4 platelet hyperactivation presence of antibody prevalent Prevent pro-inflammatory molecule Protein provided questionnaire reduced reported serum CRP sick Symptom thrombosis type 2 diabetes von Willebrand factor von Willebrand factor. vWF
[DOI] 10.1186/s12933-022-01623-4 PMC 바로가기

Diagnostic performance of molecular and serological tests of SARS-CoV-2 on well-characterised specimens from COVID-19 individuals: The EDCTP “PERFECT-study” protocol (RIA2020EF-3000)

Article

Published on 2022-09-212022-11-15
Journal: PLoS ONE
[Category] SARS, 변종, 치료기술,

[키워드] affecting Amplicon assays Biorepository Care Clinical diagnosis Clinicians collected conducted confirmed case contribute COVID-19 COVID-19 infection creating diagnosing Diagnosis effective effort ELISA ENhance Epidemiology evaluated Evidence facilitate Fatality rate Follow-up Genetic identify IMPROVE individual individuals management measure molecular Molecular assay molecular assays PCR performed platform point-of-care positive protocol real-time qPCR risk SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV2 sera Serological assay serological test Serological testing specificity specimen strain Swab transfer translate Treatment well
[DOI] 10.1371/journal.pone.0273818 PMC 바로가기

A home-based, multidisciplinary liver optimisation programme for the first 28 days after an admission for acute-on-chronic liver failure (LivR well): a study protocol for a randomised controlled trial

Article

Published on 2022-09-052022-10-05
Journal: Trials
[Category] 임상,

[키워드] 1:1 28-day mortality addition Admission Admissions Analysis Appendix 1 benefit Care changes in chronic chronic condition chronic disease chronic liver disease cirrhosis clinical Clinical improvement Clinicians Cohort conducted COVID-19 COVID-19 pandemic criteria disease evaluated exploratory subgroup analysis feasibility generalisability generate global healthcare Health Health Service health team healthcare Healthcare systems heart failure hospitalisation implementation implication include Interdisciplinary health team. interim analysis Intervention intervention arm liver Liver disease Melbourne, Australia Mortality mortality risk New outcome participant Patient performed Prevalence Primary outcome Quality of life randomisation randomised randomised controlled trial RCT readmission recruit recruited recruitment reduced reducing Registered Registration registry required resource rising robust Safe secondary severity small sample size social work Study protocol suggested Treatment Trial well WHO
[DOI] 10.1186/s13063-022-06679-x PMC 바로가기 [Article Type] Article

Influenza

Article

Published on 2022-08-272022-11-15
Journal: Lancet (London, England)
[Category] Fulltext, SARS, 치료기술,

Planning and Reporting Effective Web-Based RAND/UCLA Appropriateness Method Panels: Literature Review and Preliminary Recommendations

Article

Published on 2022-08-262022-11-16
Journal: Journal of Medical Internet Research
[Category] 변종,

[키워드] Affair approach Care category Characteristics Clinical presentations Clinicians Conducting COVID-19 pandemic Critical database de-implementation DelPhi Department Digital health elicit eligibility criteria evaluate Evidence example Guidance Health Health care health research Health technology identify IMPROVE involved less literature literature review measure medical professionals participant Planning primary care producing quality indicators RAND/UCLA appropriateness method recommendation reported Reporting reproducibility Research Research design researcher researchers review Safe Satisfaction searched seeking study outcomes the median Treatment variant veteran Virtual virtual health research Web-based. while
[DOI] 10.2196/33898 PMC 바로가기

Host Predictors of Broadly Cross-Reactive Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants of Concern Differ Between Infection and Vaccination

중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 광범위한 교차 반응성 항체의 숙주 예측 인자는 감염과 예방 접종 사이에 차이가 있습니다.

Observational Study

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 변종, 임상, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Against antibody Antibody Response B.1.1.7 B.1.351 B.1.617.2 BMI booster Clinical characteristics clinician Clinicians Cohort collected concern contributed coronavirus coronavirus 2 cross-reactive cross-reactive antibodies cross-reactive antibody disease severity enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Factor Health healthy highest Host identify IgG IgG antibodies IgG antibody IgG level immunization Immunocompromised Immunoglobulin Immunoglobulin G individual Infection information metabolic health mounted mRNA vaccination P.1 participant plasma sample plasma samples Population populations predict prospective observational cohort Protective Protective antibody RBD Receptor binding domain Regression model regression models researchers respiratory responses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant severe acute respiratory syndrome Coronavirus Spike receptor binding domain tested These data vaccination Vaccine Variability variants variants of concern variants of concern. Viral Viral variants virus variants Wuhan younger people
[DOI] 10.1093/cid/ciab996 PMC 바로가기 [Article Type] Observational Study

In silico investigation and potential therapeutic approaches of natural products for COVID-19: Computer-aided drug design perspective

Article

Published on 2022-08-222022-11-16
Journal: Frontiers in Cellular and Infection Microbiology
[Category] SARS, 신약개발,

[키워드] absence acute respiratory syndrome alkaloids analyzed anti-SARS-CoV-2 approach approved assist binding binding energy caused Clinicians Compound computer-aided drug design contribute coronavirus COVID-19 death derivative determine Diseases drug candidate drug design Drug discovery drugs effective facilitate highest in silico Ligand mechanism Medicines natural natural products Perspective pharmacological physician phytochemical Practitioner public health RdRP reported Research researcher researchers RNA polymerase Safe SARS-CoV-2 SARS-CoV-2 main protease subsequent therapeutic therapeutic approach therapeutic molecules therapeutic target took place Toxicity Treatment vaccination viral replication Virtual screening virtual screening.
[DOI] 10.3389/fcimb.2022.929430 PMC 바로가기

A Novel Benchmark Dataset for COVID-19 Detection during Third Wave in Pakistan

파키스탄의 제3의 물결 동안 COVID-19 탐지를 위한 새로운 벤치마크 데이터 세트

Article

Published on 2022-08-122022-09-11
Journal: Computational Intelligence and Neuroscience
[Category] SARS, 치료기술,